TEZSPIRE works in a unique way
Asthma Triggers

When you encounter an asthma trigger, your lungs release multiple alarmins.

Lung Icon

One of these alarmins is among the first dominoes to fall in the body’s
chain reaction and inflammatory response to asthma triggers.

Block Alarmin

TEZSPIRE works to target and block this alarmin to proactively reduce inflammation and help prevent asthma attacks.

TEZSPIRE helps to reduce inflammation brought on by your body’s overreaction to triggers.
The mechanism of action for TEZSPIRE in asthma is not fully understood.
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Before you see your doctor, it's helpful to create a personalized discussion guide with details about your asthma to see if TEZSPIRE is right for you.
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Important Safety Information

Do not use TEZSPIRE if you are allergic to tezepelumab-ekko or any of its ingredients.

Do not use to treat sudden breathing problems.

TEZSPIRE may cause serious side effects, including:

  • allergic (hypersensitivity) reactions, including anaphylaxis. Serious allergic reactions can happen after your TEZSPIRE injection. Allergic reactions can sometimes happen hours or days after you get a dose of TEZSPIRE. Call your healthcare provider or get emergency help right away if you get any of the following symptoms of an allergic reaction:
    • rash
    • breathing problems
    • hives
    • red, itchy, swollen, or inflamed eyes
    • swelling of your face, mouth, and tongue
    • fainting, dizziness, feeling lightheaded

Before using TEZSPIRE, tell your healthcare provider about all of your medical conditions, including if you:

  • have ever had a severe allergic reaction
  • have a parasitic (helminth) infection.
  • have recently received or are scheduled to receive any vaccinations. You should not receive a “live vaccine” if you are treated with TEZSPIRE.
  • are pregnant or plan to become pregnant.
  • are breastfeeding or plan to breastfeed. It is not known if TEZSPIRE passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you use TEZSPIRE.
  • are taking prescription and over-the-counter medicines, vitamins, or herbal supplements.

Do not change or stop taking your other asthma medicines unless instructed to do so by your healthcare provider.

The most common side effects of TEZSPIRE include: Sore throat, joint and back pain. These are not all the possible side effects.

APPROVED USE

  • TEZSPIRE is a prescription medicine used with other asthma medicines for the maintenance treatment of severe asthma in people 12 years of age and older whose asthma is not controlled with their current asthma medicine.
  • TEZSPIRE helps prevent severe asthma attacks (exacerbations) and can improve your breathing.
  • TEZSPIRE is not used to treat sudden breathing problems. Tell your healthcare provider if your asthma does not get better or if it gets worse after you start treatment with TEZSPIRE.
  • It is not known if TEZSPIRE is safe and effective in children under 12 years of age.

Please see full Prescribing Information, including Patient Information and Instructions for Use.

You may report side effects related to AstraZeneca products.Opens new window

Important Safety Information

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